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Single-Use Filter and Mixer

SU launch

After intense developments we are proud to announce the launch of our new Single-Use (SU) filtration and mixing solutions.

Our aim was the development of a disposable filter and a mixing solution for industries dealing with sterility and hazardous products. The simplicity of an SU equipment is well appreciated in the industry, but due to a number of shortcomings there are still many organizations who have major concerns with this technology. We at DrM, with our roots in the processing industry put all of our knowledge and expertise together to bring a fresh look into this by focusing on the process aspects and as a result developed something uniquely new.

Single-Use Filter FUNDABAC® SU

The value proposition of our FUNDABAC® Single-Use filter is its ability to reach high throughputs and increased solids capacity while maintaining high filtrate quality. This is achieved with its multi-cycle operation: Instead of running the filtration in one single cycle until the SU bag needs to be disposed, the filtered solids can be discharged from the filtering elements. They settle in the bottom where they accumulate while the regenerated filter elements can filter a second, third or any number of multiple cycles until the complete bag is filled with solids.

A high filtration flux is maintained by small cake thicknesses (traditional designs rely on thick cakes to increase solids holding capacity but sacrifice heavily of flux). With the ability to add filter aid, the flows can be increased further, however, this is not a requirement and is usually decided during testing. After the batch is processed the heel volume of the bag is simply squeezed and compacted to a minimum. This is achieved by the unique design of the filter equipment which allows air pressurization of the cavity between the SU bag and its housing.

With this patented approach we brought the concept of Single-Use filtration to a whole new level. It challenges once-through designs and sets new standards in this emerging industry.

While many users may first think of the biotech industry as the main target for such an equipment, its applications may well go beyond this traditional market. Besides typical downstream processes we had a number of very specific inquiries for toxic batches where containment of the product is of highest importance.


FUNDAMIX® SU Vibratory Mixer

The FUNDAMIX® Vibromixer has originally found its role in the biotech industry as its non-rotating agitation allows for a simple and secure sealing system in sterile applications. For the last 50 years it has provided high mixing efficiencies at low shear forces and very little energy input. It is a very mature product which now has been rejuvenated by redesigning the mixing plate for Single-Use operation.

The required changes were minimal as the FUNDAMIX® is ideally suited for Single-Use applications. However, we came up with some great designs to make the assembly of the bag in the housing as easy as possible. The drive unit itself did not require any changes but our patent includes a special docking mechanism to connect the mixing shaft to the Single-Use mixing plate.

Compared to existing Single-Use agitators the mixing intensity is significantly improved while at the same time keeping tip speeds well below what traditional agitators produce. As the amplitude is just a few Millimeter, the mixing plate can be mounted only a few Centimeter above the bottom of the Single-Use bag. This reduces liquid heel considerably and hence increases yield.

With the launch of these new products we believe to have two equipment which enrich the Single-Use industry and provide new opportunities for operators to look at their process design in a different light. The know-how of our process and development engineers can further help you enhance process design when it comes to integration of the equipment, so feel free to contact us.

FUNDAMIX® SU control
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